Protein Info for MIT1002_00151 in Alteromonas macleodii MIT1002

Annotation: putative chloramphenical resistance permease RarD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 304 transmembrane" amino acids 7 to 29 (23 residues), see Phobius details amino acids 41 to 62 (22 residues), see Phobius details amino acids 74 to 94 (21 residues), see Phobius details amino acids 106 to 123 (18 residues), see Phobius details amino acids 130 to 147 (18 residues), see Phobius details amino acids 153 to 169 (17 residues), see Phobius details amino acids 181 to 199 (19 residues), see Phobius details amino acids 211 to 233 (23 residues), see Phobius details amino acids 243 to 263 (21 residues), see Phobius details amino acids 271 to 291 (21 residues), see Phobius details PF00892: EamA" amino acids 10 to 146 (137 residues), 51.9 bits, see alignment E=4.7e-18 TIGR00688: protein RarD" amino acids 11 to 262 (252 residues), 254.6 bits, see alignment E=5.2e-80

Best Hits

Swiss-Prot: 53% identical to Y195_VIBCH: Uncharacterized transporter VC_0195 (VC_0195) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K05786, chloramphenicol-sensitive protein RarD (inferred from 96% identity to amc:MADE_00198)

Predicted SEED Role

"Protein rarD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (304 amino acids)

>MIT1002_00151 putative chloramphenical resistance permease RarD (Alteromonas macleodii MIT1002)
MSKQASAAQVGVICAIAAYSMWGVAPVYFKQLMVLPAAEILMHRVIWSVVLLVGLIAALK
QWPKVGAALRNKRVMQILFVAGLLLGANWLLFIWAINNDHILDASLGYYINPLINVFLGR
LFLGERLRNLQRVAVGLAVIGVAILIFSYGHVPWIALVLAGSFSVYGLLRKQVAVDSLPG
LFIETLMLSPFAIIYWVFFGSEYSNLFNNDATLNTLILAAGIVTTAPLLCFTAAARRIMY
STLGFFQYIGPTLMFILAVYLYGEPLEESRLVTFGFVWFALILFSADSLVNYRSQRKARK
LAVE