Protein Info for MIT1002_00084 in Alteromonas macleodii MIT1002

Annotation: Ferripyoverdine receptor precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 697 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF07715: Plug" amino acids 59 to 159 (101 residues), 56.1 bits, see alignment E=4.8e-19 TIGR01783: TonB-dependent siderophore receptor" amino acids 61 to 697 (637 residues), 270 bits, see alignment E=2.4e-84 PF00593: TonB_dep_Rec_b-barrel" amino acids 241 to 668 (428 residues), 128.6 bits, see alignment E=6.1e-41

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 94% identity to amc:MADE_00133)

Predicted SEED Role

"Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (697 amino acids)

>MIT1002_00084 Ferripyoverdine receptor precursor (Alteromonas macleodii MIT1002)
MKLSSLFALTPIAFALSVNAQTTQSDTVEVKEADVEKIRIVGVRQNRVSRGATGLTMEIS
ETPQSISILSEDLMQSFGAFNINDALKLAPGINVEEWETNRTNYTARGFEIKNTQIDGVG
LPNDWGIVTGSVEAYGYEEIEVIRGANGLLTGVGNASGTINYVRKRPTNEEGGEVGASVG
SYNFKRVQGDYSMLLTEDGSWAARVVGSFEDKESHLDGLENDRGFVYGVIDGQLTDNATI
TFGLSYQDANTDGNTWGGLVFNYTDGTQAEWDINDTTTQEWTKWDTETTNAFVELDYEFD
NDWQLLLSYNFRGYEDESKLFYAYGAIDKETGLGLVGWPGRYDSEIDSHLLEGRVFGDFE
LFGRSHEVNFGVSHATSDDVSFVHAFDYATTPAYGPTPAFPYGLDAIAEPEWLGVSEYSN
IEQTLTRYFGSARFSVTDEMHIIAGFNAIDFERTGQNAGAVIDNSESEASPYVGATYAVT
EDVNAYVSYSDVYQPQEQYDVNGQYLDPTKGKNFEAGFKAQWFDDRLLTTFAYFTAEQDN
LAAYAGTNPETLQYYYKGVSVESDGFEIELAGQLTDDLRINASYTNIDVEDEQGNDANLW
APRDVVTFQLGYTVPQAPEIEVGFGGRWQSEISNVDYNVKQGAYFLGNVYASHAFTEDFT
VRMNINNIFDKKYINSLHTVGYYGAGINAQLSASYTF