Protein Info for MIT1002_00013 in Alteromonas macleodii MIT1002

Annotation: putative GTP-binding protein EngB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 211 transmembrane" amino acids 127 to 144 (18 residues), see Phobius details TIGR03598: ribosome biogenesis GTP-binding protein YsxC" amino acids 7 to 191 (185 residues), 240.7 bits, see alignment E=4.6e-76 PF01926: MMR_HSR1" amino acids 26 to 144 (119 residues), 68.9 bits, see alignment E=2.1e-23

Best Hits

Swiss-Prot: 93% identical to ENGB_ALTMD: Probable GTP-binding protein EngB (engB) from Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)

KEGG orthology group: K03978, GTP-binding protein (inferred from 93% identity to amc:MADE_00015)

Predicted SEED Role

"GTP-binding protein EngB" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (211 amino acids)

>MIT1002_00013 putative GTP-binding protein EngB (Alteromonas macleodii MIT1002)
MSYYTKAKFFTSAPDIRHLKNDTGIEVAFAGRSNAGKSSALNTLTRQKNLARTSKTPGRT
QLINVFELEEDLRLVDLPGYGFAKVPVAMKKKWQASLGEYLQKRKSLKGLVVLMDIRHPF
KDLDQDLIHWAVASNIPVLALLTKADKLKSGKRKAQLLMAREAAMAFMGDVTVQTFSSLN
KHGLPELERILDTWFGLDKQDETEESDSEVQ