Protein Info for MCAODC_20405 in Escherichia coli ECRC101

Name: yeeY
Annotation: Uncharacterized HTH-type transcriptional regulator YeeY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 PF00126: HTH_1" amino acids 13 to 70 (58 residues), 49.9 bits, see alignment E=2.4e-17 PF03466: LysR_substrate" amino acids 96 to 298 (203 residues), 97.8 bits, see alignment E=6.1e-32

Best Hits

Swiss-Prot: 99% identical to YEEY_ECOLI: Uncharacterized HTH-type transcriptional regulator YeeY (yeeY) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to ssn:SSON_2085)

Predicted SEED Role

"Hypothetical transcriptional regulator yeeY"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (316 amino acids)

>MCAODC_20405 Uncharacterized HTH-type transcriptional regulator YeeY (Escherichia coli ECRC101)
MHCKGACMKPLLDVLMILDALEKEGSFAAASAKLYKTPSALSYTVHKLESDLNIQLLDRS
GHRAKFTRTGKMLLEKGREVLHTVRELEKQAIKLHEGWENELVIGVDDTFPFSLLAPLIE
AFYQHHNVTRLKFINGVLGGSWDALTQGRADIIVGAMHEPPSSSEFGFSRLGDLEQVFAV
APHHPLAQEEEPLNRRIIKRYRAIVVGDTAQAGASTASQLLDEQEAITVFDFKTKLELQI
SGLGCGYLPRYLAQRFLDSGALIEKKVVAQTLFEPVWIGWNEQTAGLASGWWRDEILANS
AIAGVYAKSDDGKSAI