Protein Info for MCAODC_20075 in Escherichia coli ECRC101

Annotation: protein hokC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 70 transmembrane" amino acids 25 to 43 (19 residues), see Phobius details PF01848: HOK_GEF" amino acids 25 to 66 (42 residues), 78.1 bits, see alignment E=1.5e-26

Best Hits

Swiss-Prot: 70% identical to MOKC_ECOLI: Regulatory protein MokC (mokC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 96% identity to eoi:ECO111_1062)

Predicted SEED Role

"RelF inactive antibacterial toxin protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (70 amino acids)

>MCAODC_20075 protein hokC (Escherichia coli ECRC101)
MLHKRRLASYAPKGKEKQVMKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEV
AVFTAYEPEE