Protein Info for MCAODC_19820 in Escherichia coli ECRC101

Name: hchA
Annotation: protein deglycase HchA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.

Best Hits

Swiss-Prot: 100% identical to HCHA_ECO57: Protein/nucleic acid deglycase HchA (hchA) from Escherichia coli O157:H7

KEGG orthology group: K05523, molecular chaperone HchA (Hsp31) (inferred from 100% identity to eco:b1967)

MetaCyc: 100% identical to protein/nucleic acid deglycase 1 (Escherichia coli K-12 substr. MG1655)
GLYOXIII-RXN [EC: 4.2.1.130]; RXN-17630 [EC: 4.2.1.130, 3.5.1.124]; 3.5.1.124 [EC: 4.2.1.130, 3.5.1.124]; 3.5.1.124 [EC: 4.2.1.130, 3.5.1.124]

Predicted SEED Role

"Chaperone protein hchA"

MetaCyc Pathways

• methylglyoxal degradation IX (1/1 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.124 or 4.2.1.130

Protein Sequence (283 amino acids)

>MCAODC_19820 protein deglycase HchA (Escherichia coli ECRC101)
MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERY
LPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPQKDEKVMPFF
EQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRF
VISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGM
NIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQEMLAAYAG