Protein Info for MCAODC_16400 in Escherichia coli ECRC101

Annotation: Putative inner membrane exporter, YdcZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 149 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 34 to 55 (22 residues), see Phobius details amino acids 69 to 88 (20 residues), see Phobius details amino acids 94 to 115 (22 residues), see Phobius details amino acids 126 to 145 (20 residues), see Phobius details PF04657: DMT_YdcZ" amino acids 6 to 143 (138 residues), 85.5 bits, see alignment E=2.2e-28

Best Hits

Swiss-Prot: 99% identical to YDCZ_ECOLI: Inner membrane protein YdcZ (ydcZ) from Escherichia coli (strain K12)

KEGG orthology group: K09936, hypothetical protein (inferred from 99% identity to eco:b1447)

Predicted SEED Role

"Putative inner membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (149 amino acids)

>MCAODC_16400 Putative inner membrane exporter, YdcZ (Escherichia coli ECRC101)
MNQSLTLAFLIAAGIGLVVQNSLMVRITQTSSTILIAMLLNSLVGIVLFVSILWFKQGMA
GFGELVSSVRWWTLIPGLLGSFFVFASISGYQNVGAATTIAVLVASQLIGGLVLDIFRSH
GVPLRALFGPICGAILLVVGAWLVARRSF