Protein Info for MCAODC_13000 in Escherichia coli ECRC101

Name: cscK
Annotation: aminoimidazole riboside kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00294: PfkB
  • amino acids 3 to 298 (296 residues), 221.5 bits, E=8.1e-70

Best Hits

Swiss-Prot: 99% identical to SCRK_ECOLX: Fructokinase (cscK) from Escherichia coli

KEGG orthology group: K00847, fructokinase [EC: 2.7.1.4] (inferred from 98% identity to ecp:ECP_2387)

MetaCyc: 62% identical to fructokinase (Klebsiella pneumoniae)
Fructokinase. [EC: 2.7.1.4]

Predicted SEED Role

"Fructokinase (EC 2.7.1.4)" in subsystem Fructose utilization or Mannitol Utilization or Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization or Sucrose utilization or Sucrose utilization Shewanella (EC 2.7.1.4)

MetaCyc Pathways

• superpathway of anaerobic sucrose degradation (17/19 steps found)
• heterolactic fermentation (16/18 steps found)
• sucrose degradation III (sucrose invertase) (4/4 steps found)
• sucrose degradation IV (sucrose phosphorylase) (4/4 steps found)
• D-sorbitol degradation I (3/3 steps found)
• mannitol cycle (4/5 steps found)
• sucrose degradation II (sucrose synthase) (4/5 steps found)
• sucrose degradation I (sucrose phosphotransferase) (1/3 steps found)
• sucrose degradation VII (sucrose 3-dehydrogenase) (1/4 steps found)

KEGG Metabolic Maps

• Fructose and mannose metabolism
• Nucleotide sugars metabolism
• Starch and sucrose metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.4

Use Curated BLAST to search for 2.7.1.4

Protein Sequence (304 amino acids)

>MCAODC_13000 aminoimidazole riboside kinase (Escherichia coli ECRC101)
MSAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGTSGFIGRVGDDPFGALM
QRTLLTEGVDITYLKQDEWHRTSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPCWRHG
EWLHLCSIALSAEPSRTSAFTAMTEIRHAGGFVSFDPNIREDLWQDEHLLRLCLRQALQL
ADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAGMS
VDCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTALPCR
QELE