Protein Info for MCAODC_04930 in Escherichia coli ECRC101

Name: yigA
Annotation: Uncharacterized protein YigA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 235 PF04340: DUF484" amino acids 11 to 232 (222 residues), 296.3 bits, see alignment E=8.4e-93

Best Hits

Swiss-Prot: 99% identical to YIGA_ECOLI: Uncharacterized protein YigA (yigA) from Escherichia coli (strain K12)

KEGG orthology group: K09921, hypothetical protein (inferred from 99% identity to eco:b3810)

Predicted SEED Role

"Protein of unknown function DUF484"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (235 amino acids)

>MCAODC_04930 Uncharacterized protein YigA (Escherichia coli ECRC101)
MKQPGEELQETLTELDDRVVVDYLIKNPEFFIRNARAVEAIRVPHPVRGTVSLVEWHMAR
ARNHIHVLEENMALLMEQALANEGLFYRLLYLQRSLTAASSLDDMLMRFHRWARDLGLAG
ASLRLFPDRWRLGAPSNHTHLALSRQSFEPLRIQRLGQEQHYLGPLNGPELLVVLPEAKA
VGSVAMSMLGSDADLGVVLFTSRDASHYQQGQGTQLLHEIALMLPELLERWIERV