Protein Info for MCAODC_04435 in Escherichia coli ECRC101

Name: frvX
Annotation: aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 356 PF05343: Peptidase_M42" amino acids 43 to 333 (291 residues), 336.1 bits, see alignment E=7.8e-105

Best Hits

Swiss-Prot: 96% identical to FRVX_ECOLI: Putative aminopeptidase FrvX (frvX) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ece:Z5441)

Predicted SEED Role

"FIG00638402: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (356 amino acids)

>MCAODC_04435 aminopeptidase (Escherichia coli ECRC101)
MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGSFVARKGNKGPKVAVVG
HMDEVGFMVTHIDESGFLRFTTIGGWWNQSMLNHRVTIRTHKGVKIPGVIGSVAPHALTE
KQKQQPLSFDEMFIDIGANSREEAKKRGAEIGDFISPEANFACWGEDKIVGKALDNRIGC
AMMAELLQTVNNPGITLYGVGSVEEEVGLRGAQTSAEHTKPDVVIVLDTAVAGDVPGIDN
IKYPLKLGNGPGLMLFDKRYLPNQKLVAALKNCAAHNGLPLQFSTMKTGATDGGRYNVMG
GGRPVVALCLPTRYLHANSGMISKADYDALLTLIRDFLTTLTAEKVNAFSQFRQVD