Protein Info for M666_RS20120 in Cellulophaga baltica 18

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 525 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 281 to 302 (22 residues), see Phobius details PF21623: HK_sensor_dom_bact" amino acids 70 to 194 (125 residues), 30.6 bits, see alignment E=3.8e-11 PF07536: HWE_HK" amino acids 328 to 381 (54 residues), 24.8 bits, see alignment 6.1e-09 PF07568: HisKA_2" amino acids 328 to 401 (74 residues), 99 bits, see alignment E=2.7e-32 PF02518: HATPase_c" amino acids 427 to 519 (93 residues), 43.2 bits, see alignment E=9.9e-15

Best Hits

KEGG orthology group: None (inferred from 76% identity to cao:Celal_0201)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (525 amino acids)

>M666_RS20120 sensor histidine kinase (Cellulophaga baltica 18)
MSKKLIATSIALVVILSVAIWVITVIRINKYEKNLSAIELADSEAELSAAHEHLLNLYDT
SRKKVLFFKDLVEANYNQTKSFKEVGPIFYYFLKNEDDYFQARIIDPDGKELLKVENMYN
SVSIYENKYLEDKSNRYYVQKTLRLKKGQIFVSNIDLNIENNIIETPYRPTVRFFTKLFD
ADNNLLGIVGLNLNAATWLNGIGSKNINILNNASEIFYNENNKNELYTKSSVDLTEKDGN
GNPIYNVKKITIAGMSDWTLYTTMHSPEVHRKIKVNKKNTVYFSIFLNLGLLFFMFTIHN
LYYKNKHISSLNNAINLRLEERNTLLKEIHHRVKNNLQVITSLLNLQSRYIQDEDVKSML
KYSQYRIKSMALLHESLYRSDDLSKINYADYLKQLVNGLIISMKGSTNKITLDLEVDEIY
FNIDTSIPLGLIINELVTNSLKYAFSDNIGTITISLKKQANNSFLLHIGDNGKGFPKTVK
FRDTDTLGLKLVHKLVLQLNGNIEKDNLQTGTTFIITFQEIQELS