Protein Info for LU632_RS25880 in Erwinia tracheiphila SCR3

Name: traH
Annotation: F-type conjugal transfer protein TraH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF06122: TraH" amino acids 29 to 375 (347 residues), 367 bits, see alignment E=6.5e-114

Best Hits

Swiss-Prot: 57% identical to TRAH1_ECOLI: Protein TraH (traH) from Escherichia coli (strain K12)

KEGG orthology group: K12072, conjugative transfer pilus assembly protein TraH (inferred from 62% identity to asa:ASA_P5G038)

Predicted SEED Role

"IncF plasmid conjugative transfer pilus assembly protein TraH" in subsystem Type 4 secretion and conjugative transfer

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (454 amino acids)

>LU632_RS25880 F-type conjugal transfer protein TraH (Erwinia tracheiphila SCR3)
MNGGLRKSALACVLCLYTLMAGASLNDDMNKFFGKLGYEQNTTTPKVWQGQAAGYATGGA
LYARTSAKDVQLVSLQLPSLNAGCGGIDMFLGSFSFISKDEFIQFAKSILSNAPGLFFDL
ALKTVTPQLASAKDFLQKLASDVNSSNMSSCQAARAIVGGLWPETQENASAVCQTIGSDS
NFFSDWAAARQGCGTGGQYKNMSNKAGADMKDQVLRNKNLIWDSLEKNQVFSGNKELKEF
AMSITGTLIFDDDGKPQPLTAMTTNEDLIHALLHGGTAKIYTCNDGDCLKATIGEVTISA
ENSLSGQVNKMLQSIGSKAYADEALTEKEKGFITSTSVPVLRYLVDPLSLGVSDSVIYQL
SDYISFDILIQYMQEVMQQARVMLASKSYPDSALKPLQESMANANRQLAIMQSRVQVQQD
ALMVVERQMGYMRQQLSGRLLDRYQNNYRFSGGM