Protein Info for LU632_RS22765 in Erwinia tracheiphila SCR3

Name: tauA
Annotation: taurine ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 318 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF04069: OpuAC" amino acids 18 to 222 (205 residues), 87.5 bits, see alignment E=2.3e-28 TIGR01729: taurine ABC transporter, periplasmic binding protein" amino acids 19 to 314 (296 residues), 457.3 bits, see alignment E=1.3e-141 PF13379: NMT1_2" amino acids 19 to 233 (215 residues), 66 bits, see alignment E=9.8e-22 PF12974: Phosphonate-bd" amino acids 31 to 210 (180 residues), 36.3 bits, see alignment E=8.6e-13 PF09084: NMT1" amino acids 32 to 235 (204 residues), 66.5 bits, see alignment E=6.6e-22

Best Hits

Swiss-Prot: 74% identical to TAUA_ECOLI: Taurine-binding periplasmic protein (tauA) from Escherichia coli (strain K12)

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 84% identity to ebi:EbC_41560)

MetaCyc: 74% identical to taurine ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-64-RXN [EC: 7.6.2.7]

Predicted SEED Role

"Taurine-binding periplasmic protein TauA" in subsystem Taurine Utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (318 amino acids)

>LU632_RS22765 taurine ABC transporter substrate-binding protein (Erwinia tracheiphila SCR3)
MTTMLALFSCMSGAKAVDVTIAYQTSAEPAKVAQANNTFAKESGVKADWRKFDSGSSVVR
ALASGDIQIGNIGSSPLAVAASQQVPIEVFLLASQLGSSEALVVRKGINNPQDLVGKRIA
VPFISTTHYSLLAALKHWGIAPDKVQILNLQPPEIIAAWQQGDIDGAYVWAPAVTELEKN
GSVLTDSAQVGKWGSPTLDVWVVRKDFAQQHPDVVAAFARSAIAAQKGYLDNPEQWLKNN
ENLSTLSRLSGVPAQQVPQLVRGNNYLTARQQVEQLGQPVNQAIIDTATFLKAQGKVPQV
ASDYSGYVTDRFVKSLAQ