Protein Info for LU632_RS22725 in Erwinia tracheiphila SCR3

Name: slyD
Annotation: peptidylprolyl isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00254: FKBP_C
  • amino acids 4 to 77 (74 residues), 30.8 bits, E=1.6e-11

Best Hits

Swiss-Prot: 85% identical to SLYD_ECOL6: FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (slyD) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K03775, FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC: 5.2.1.8] (inferred from 87% identity to ebi:EbC_41440)

MetaCyc: 85% identical to FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (Escherichia coli K-12 substr. MG1655)
Peptidylprolyl isomerase. [EC: 5.2.1.8]; RXN-22956 [EC: 5.2.1.8]

Predicted SEED Role

"FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase or Potassium homeostasis (EC 5.2.1.8)

MetaCyc Pathways

• NiFe(CO)(CN)₂ cofactor biosynthesis (1/10 steps found)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Protein Sequence (173 amino acids)

>LU632_RS22725 peptidylprolyl isomerase (Erwinia tracheiphila SCR3)
MKVAKDLVVSLAYQVRTEEDVLVDESTVSAPLDYLHGHGSLIVGLEKALENHEAGDKFEV
NIAADDAYGQYDDNLVQRVSKDVFMGVDELQVGMRFLAETDQGSVPVEITEVEDDHVVVD
GNHTLAGQNLNFKVEVVEIREATPEELAHGHVHGAHDHHHDHEHGQGGCGCSH