Protein Info for LU632_RS22325 in Erwinia tracheiphila SCR3

Name: plsB
Annotation: glycerol-3-phosphate 1-O-acyltransferase PlsB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03703: glycerol-3-phosphate O-acyltransferase
  • amino acids 12 to 800 (789 residues), 1169.9 bits, E=0
• PF01553: Acyltransferase
  • amino acids 283 to 425 (143 residues), 98.7 bits, E=2.4e-32
• PF19277: GPAT_C
  • amino acids 436 to 772 (337 residues), 368.1 bits, E=5.1e-114

Best Hits

Swiss-Prot: 79% identical to PLSB_ESCF3: Glycerol-3-phosphate acyltransferase (plsB) from Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)

KEGG orthology group: K00631, glycerol-3-phosphate O-acyltransferase [EC: 2.3.1.15] (inferred from 90% identity to ebi:EbC_03060)

MetaCyc: 78% identical to glycerol-3-phosphate 1-O-acyltransferase (Escherichia coli K-12 substr. MG1655)
Glycerol-3-phosphate O-acyltransferase. [EC: 2.3.1.15]; 2.3.1.15 [EC: 2.3.1.15]; 2.3.1.15 [EC: 2.3.1.15]; 2.3.1.15 [EC: 2.3.1.15]; 2.3.1.15 [EC: 2.3.1.15]

Predicted SEED Role

"Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.3.1.15)

MetaCyc Pathways

• superpathway of phospholipid biosynthesis III (E. coli) (11/12 steps found)
• phosphatidylglycerol biosynthesis I (6/6 steps found)
• phosphatidylglycerol biosynthesis II (6/6 steps found)
• CDP-diacylglycerol biosynthesis I (4/4 steps found)
• CDP-diacylglycerol biosynthesis II (4/4 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (10/13 steps found)
• oleate biosynthesis III (cyanobacteria) (2/3 steps found)
• phosphatidate biosynthesis (yeast) (3/5 steps found)
• diacylglycerol and triacylglycerol biosynthesis (3/7 steps found)
• palmitoyl ethanolamide biosynthesis (2/6 steps found)
• superpathway of stearidonate biosynthesis (cyanobacteria) (2/6 steps found)
• stigma estolide biosynthesis (2/7 steps found)
• anandamide biosynthesis II (2/8 steps found)
• anandamide biosynthesis I (4/12 steps found)
• superpathway of phospholipid biosynthesis II (plants) (10/28 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism
• Glycerophospholipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.15

Use Curated BLAST to search for 2.3.1.15

Protein Sequence (806 amino acids)

>LU632_RS22325 glycerol-3-phosphate 1-O-acyltransferase PlsB (Erwinia tracheiphila SCR3)
MSGWRSFYYNTLNLPVKVLVRSKAIPKDPITELGLDTSRPIMYVLPYDSKADLLALREQC
RKQELPDPLKPLEIDGTVLPRHVFIHDGPRLFPYFVPNLESVRLFHDYLDLHRSNPHLDV
QMVPVSVMFGRAPGREIQGEEQPHLRMLNGIQKFCAVLWLGRDSFVRFSPMVSMRRMATE
HGTDKTIAQKLARVARIHFARQRLAAIGPRLPVRQDLFNKLLQSKAIVKAIEDEARGKKI
SLDKAQQNAVELMEEIAADFSYEAIRLTDRVMGWLWSKLYQGINVNGGERVRQLAQDGHE
IVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGQIFRRLGAFFIRRTFKGN
KLYSTVFREYLGELFTRGYSIEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGNRPITL
VPIYIGYEHVMEVSTYAKELRGATKEKEGFMQMVRGLRKLRNLGQGYVNFGEPLPLVSYL
NRQVPEWREAIDPLEAQRPAWLAPAVNDIAQRMMVRINNAGAANAMNLCVTALLASRQRS
LTREQMIDQLDCYTQLLRNVPYSPDATVPDLTPEKLLDHALGMNKFEIEQDNIGEIIGLP
REQAVLMTYYRNNIHHMLVMPSVIAVILTQHREVTRAELLRQVSVIYPMLKSELFLRWEK
DELPVLLDALIGEMAHQGLLNADEQALRLSALRFHTLQLLAAGVRETLQRYAITFSILSA
NPSINRGTLEKESRTMAQRLSVLHGINAPEFFDKAVFSTLVLTLRDEGYISDTGDALVEE
THKVYQMLADLITHEVRMTIESAVAQ