Protein Info for LU632_RS20990 in Erwinia tracheiphila SCR3
Annotation: GIY-YIG nuclease family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 62% identical to Y453_YERE8: UPF0213 protein YE0453 (YE0453) from Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
KEGG orthology group: K07461, putative endonuclease (inferred from 68% identity to eta:ETA_03560)MetaCyc: 52% identical to DNA damage response nuclease YhbQ (Escherichia coli K-12 substr. MG1655)
Exodeoxyribonuclease I. [EC: 3.1.11.1]
Predicted SEED Role
"FIG137864: putative endonuclease containing a URI domain" in subsystem CBSS-214092.1.peg.3450
Isozymes
Compare fitness of predicted isozymes for: 3.1.11.1
Use Curated BLAST to search for 3.1.11.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (104 amino acids)
>LU632_RS20990 GIY-YIG nuclease family protein (Erwinia tracheiphila SCR3) MTQMKNDSETSWRLYILRTRHGLLYTGITNDISRRVDQHQRGKGAKALRGKGPLELMFHC EAGDRSSASKLEYQVKRLMREDKLRLIIHQPASLIQWLNTLKGR