Protein Info for LU632_RS20890 in Erwinia tracheiphila SCR3

Name: kup
Annotation: low affinity potassium transporter Kup

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 621 signal peptide" amino acids 8 to 9 (2 residues), see Phobius details transmembrane" amino acids 10 to 28 (19 residues), see Phobius details amino acids 49 to 72 (24 residues), see Phobius details amino acids 93 to 113 (21 residues), see Phobius details amino acids 134 to 155 (22 residues), see Phobius details amino acids 167 to 188 (22 residues), see Phobius details amino acids 202 to 231 (30 residues), see Phobius details amino acids 244 to 268 (25 residues), see Phobius details amino acids 287 to 311 (25 residues), see Phobius details amino acids 336 to 356 (21 residues), see Phobius details amino acids 363 to 386 (24 residues), see Phobius details amino acids 393 to 416 (24 residues), see Phobius details amino acids 422 to 440 (19 residues), see Phobius details PF02705: K_trans" amino acids 13 to 543 (531 residues), 686.7 bits, see alignment E=1e-210

Best Hits

Swiss-Prot: 59% identical to KUP_SALSV: Low affinity potassium transport system protein kup (kup) from Salmonella schwarzengrund (strain CVM19633)

KEGG orthology group: None (inferred from 83% identity to pao:Pat9b_0422)

MetaCyc: 59% identical to K+:H+ symporter Kup (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-3

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (621 amino acids)

>LU632_RS20890 low affinity potassium transporter Kup (Erwinia tracheiphila SCR3)
MTSKKQPLPAAMMAAVGIVFGDIGTSPLYTLKECLSILPAGGTTETAVMGFLSLIFWGLT
LIVTIKYVCFVMRADVDGEGGIMTLMSLARQSVSGRAVHLIVLAGLTGGAFFYGDGVITP
AISVMSAIEGIEVVAPALDRFIVPLSVVILALLFIIQKHGTERVSRVFGPVMLVWFVTLA
ALGLRGIMMNPGVLHALNPAFALAFLLSHKALSFAALGMVVLAVTGAEALYADMGHLGKM
PIRMAWLIIAMPSLVLNYFGQGALVLAMSDAVKNPFYILAPGWAQIPLIVLSTLATVIAA
QSIITGVYTLTHQAIRQSFLPPMRIVYTSSTESGQIYIPVVNWLLFIAVTLIIVAFKSSS
ALSAAYGIVVTGTMVLTAFLTGIVAFRKWKWPLPVALIFLLCMLVIDVTLFGANLIKLLS
GGWVPVLLAMVMLVLMLIWSSERSRLIRRLSDDPESLRAIINSLEASPPKRVAGTAIFLT
KKVSEIPQALLHNLKHNRVMHERIVLLHIRTTDKPREYNQNRIALQQLSPTFWQVTASYG
WHEVPAMQEILYLCGLEGFGCTVNEASFFTSHDTLIMKKRRGLSRLKGGIFHFFQHNALR
AHEQFMIPPNRVIELGGQKEF