Protein Info for LU632_RS20550 in Erwinia tracheiphila SCR3

Annotation: DedA family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 transmembrane" amino acids 24 to 60 (37 residues), see Phobius details amino acids 68 to 87 (20 residues), see Phobius details amino acids 121 to 143 (23 residues), see Phobius details amino acids 155 to 175 (21 residues), see Phobius details amino acids 187 to 212 (26 residues), see Phobius details PF09335: SNARE_assoc" amino acids 48 to 173 (126 residues), 71.3 bits, see alignment E=5.3e-24

Best Hits

Swiss-Prot: 67% identical to YGHB_ECOLI: Inner membrane protein YghB (yghB) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 81% identity to ebi:EbC_38260)

Predicted SEED Role

"DedA family inner membrane protein YghB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (218 amino acids)

>LU632_RS20550 DedA family protein (Erwinia tracheiphila SCR3)
MAVLHEIIQALWRQDFAALANPDVIYVVYSIMFMTLLLENGLLPAAFLPGDSLLLLAGAM
IARGAMDFMPSIIILTLAASLGYWLSYLQGRWLGNTRLVKSWLLHLPVQYHQRAWNLFHR
YGLMALLVGRFLAFVRTILPTMAGISGLNNTRFQIFNWLSGLLWVGILVTLGYTISHVPF
IKRHEDVLMTILMVLPLILLCIGVLGSVMIMLKRKKSL