Protein Info for LU632_RS20440 in Erwinia tracheiphila SCR3

Name: btsR
Annotation: two-component system response regulator BtsR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 242 PF00072: Response_reg" amino acids 4 to 110 (107 residues), 81.3 bits, see alignment E=5.9e-27 PF04397: LytTR" amino acids 142 to 235 (94 residues), 82 bits, see alignment E=3.1e-27

Best Hits

Swiss-Prot: 74% identical to BTSR_SHIFL: Transcriptional regulatory protein BtsR (btsR) from Shigella flexneri

KEGG orthology group: K02477, two-component system, LytT family, response regulator (inferred from 74% identity to cro:ROD_22381)

Predicted SEED Role

"Two-component response-regulatory protein YehT"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (242 amino acids)

>LU632_RS20440 two-component system response regulator BtsR (Erwinia tracheiphila SCR3)
MLRVVIVDDEPLARANLRLMLMEEPDITIVSECVNAIEAIGAVHRLKPDVLFLDIQMPRI
NGLEMVSMLDDSHRPFIVFLTAFEEYALKAFEEHAFDYLLKPVASARLGKTLMRLRQQRQ
VLPAPQEHPQPLQFIPCSGHSRIYLLQIHDVAFVSCRMSGVYVTDNQGKEGLTELTLRTI
ENRTTFLRCHRQYLVNMAQLKEICLQDNGQAELKLRCGLTVPVSRRYLKPLKKAWGYRHH
PS