Protein Info for LU632_RS20360 in Erwinia tracheiphila SCR3

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 797 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF07715: Plug" amino acids 67 to 192 (126 residues), 50.5 bits, see alignment E=2.8e-17 PF00593: TonB_dep_Rec" amino acids 279 to 754 (476 residues), 142.8 bits, see alignment E=3.1e-45

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 76% identity to ebi:EbC_37650)

Predicted SEED Role

"TonB-dependent hemin , ferrichrome receptor" in subsystem Hemin transport system or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (797 amino acids)

>LU632_RS20360 TonB-dependent receptor (Erwinia tracheiphila SCR3)
MRNLISSKGIVRTSVLCSTLVISGYSIEAESTNTSLQPVNTSDKSRTVSTHADVAEPEMV
VTAPVLKKEAGSKTVVSAEEMQKKGTNDFGSVMRYEPLISAIGASGGSSAGKSGFDRSGY
TGYNIRGLESNRVGLDVDGIPQPEATGRSYAGRVGVNTFGIGRDYIDPYMYGQVDIESGA
TSTAWANNAIGGSVSFMPKSADDYLSPNKLTYFGDQSDYDSANRSWHNGITIAAGDETLR
GVFVYSRRDGQQTRNNSGTLAAYPANWYSNAMLASGIWRPNDQHKLTGTVDYYDKTNHTH
FDSWNSAGSAIWGTAQQQSNTRRWGFSLKDEWTPVNAFADSLTSRVYYQQTQAHDNTWMP
SSATAMQRVYSNYDVDTYGFETQLTKSLRRHDLSGGLNASTSDTTRPFRQSPAPSQFTVI
MQPQADSRSYMLGGYLQDQIHFDLDGHDFSIVPGVRIAHQTTKPQNLYSLTTGSAVLTES
QLQTLYGKANADTQVLPSLSFNYDLTPQLMTYVMYKRGTQFPGASQLFGSWNLGSSYAGS
QQYALIGNSDLKTETSKNVEWGLKGQAVEGVTLNAAMFYNTYENFIAYTRYTRAVHPGMF
SNVPSNIYTIFQAENRDKAYIYGGQVSTKVNFGTWFEQVDGLSTTFALGYTQGKSKSSYA
GDQYVDLDSVAPMKAIVGVAWDDPAKRYGTAVTATFVKGKRAMETNREAYTNSGSVLTEA
SGEFMRVPGYGLLDMTAYWQVAKNVRVNGGIYNLTDRKYWDYLSSRNLTESTLQDAYDKA
LAVMPGRTFLLGMNIDF