Protein Info for LU632_RS20045 in Erwinia tracheiphila SCR3

Name: fhuB
Annotation: Fe(3+)-hydroxamate ABC transporter permease FhuB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 649 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 46 to 66 (21 residues), see Phobius details amino acids 78 to 97 (20 residues), see Phobius details amino acids 105 to 125 (21 residues), see Phobius details amino acids 132 to 152 (21 residues), see Phobius details amino acids 181 to 200 (20 residues), see Phobius details amino acids 212 to 230 (19 residues), see Phobius details amino acids 236 to 253 (18 residues), see Phobius details amino acids 265 to 286 (22 residues), see Phobius details amino acids 292 to 311 (20 residues), see Phobius details amino acids 336 to 357 (22 residues), see Phobius details amino acids 381 to 401 (21 residues), see Phobius details amino acids 413 to 431 (19 residues), see Phobius details amino acids 437 to 457 (21 residues), see Phobius details amino acids 469 to 488 (20 residues), see Phobius details amino acids 510 to 528 (19 residues), see Phobius details amino acids 533 to 538 (6 residues), see Phobius details amino acids 557 to 583 (27 residues), see Phobius details amino acids 595 to 615 (21 residues), see Phobius details amino acids 620 to 644 (25 residues), see Phobius details PF01032: FecCD" amino acids 3 to 311 (309 residues), 225.7 bits, see alignment E=3.7e-71 amino acids 345 to 646 (302 residues), 226 bits, see alignment E=3e-71

Best Hits

Swiss-Prot: 67% identical to FHUB_ECOLI: Iron(3+)-hydroxamate import system permease protein FhuB (fhuB) from Escherichia coli (strain K12)

KEGG orthology group: K02015, iron complex transport system permease protein (inferred from 77% identity to ebi:EbC_07960)

MetaCyc: 67% identical to iron(III) hydroxamate ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-11-RXN [EC: 7.2.2.16]; TRANS-RXN-297 [EC: 7.2.2.16]; TRANS-RXN-298 [EC: 7.2.2.16]

Predicted SEED Role

"Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), permease component FhuB" in subsystem Iron acquisition in Vibrio or Siderophore Aerobactin (TC 3.A.1.14.3)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (649 amino acids)

>LU632_RS20045 Fe(3+)-hydroxamate ABC transporter permease FhuB (Erwinia tracheiphila SCR3)
MLILAAVLALTFYNFNQQLPATQWLAALHAADPDQVDQMVFHYSLMPRLVLSLLVGGGLG
LVGVLFQQVLRNPLAEPGTLGVATGAQLGLTIATLWSLPGGLFSQQMAAMAGAIFVAMVV
FGIAWGKRLSPVTLILAGLVMSLYCGAANQLLRLFNHDRLQNIFLWSTGTLNQMDWHNVS
FLWPKLLIGLLLSLVMIRPMTLLGLDDGVAKNLGLSLALSRIGVLALAVVLSAQLVNAVG
IISFIGLFAPLLAKMLGVRRLPCRLLLATLIGMLLLWLADQGVIWLTARWRAVSTGTATA
IIGAPLLLWLLPRLKMTAVIPAINQGDNVPLERHRVAIWASLAAVLLLVLGVAAVSLGRD
AHGWHWATGELWQQLMPWRLPRMAAALTTGMMLGVAGCIVQRLTGNPMASPEVLGISTGA
VFGVVVMLFIVPGYAFGWLLPAGCLGAALTLLAIATIGGRGGFSPERMLLAGMALSTVFS
TLLLLLLASGDPRMATLMTWIAGSTYHVDAAGAGRTALITAILLGLTPLCRRWLMLLPLG
SETARAVALALRPARMALLLLAAALTAAATLTTGPLSFVGLMAPHIARMLGFRRALPQLI
MAAFLGGGLMTLADWCGRMIAFPAQIPAGLLATFIGAPYFVWLLRKVQA