Protein Info for LU632_RS19290 in Erwinia tracheiphila SCR3

Annotation: DUF1145 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 89 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 34 to 53 (20 residues), see Phobius details amino acids 62 to 81 (20 residues), see Phobius details PF06611: DUF1145" amino acids 1 to 57 (57 residues), 80.7 bits, see alignment E=2.8e-27

Best Hits

Swiss-Prot: 65% identical to YHHL_ECOLI: Uncharacterized protein YhhL (yhhL) from Escherichia coli (strain K12)

KEGG orthology group: K08993, putative membrane protein (inferred from 75% identity to eta:ETA_32790)

Predicted SEED Role

"Putative inner membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (89 amino acids)

>LU632_RS19290 DUF1145 family protein (Erwinia tracheiphila SCR3)
MLINLGRLLMVFVWGFLLLNLVHAFPRPLKYFVDVALIFMVIMHAVQLVLLRATQPKTGP
TLSGLTQAKIFFFGVFELLLWQKKNMPKK