Protein Info for LU632_RS19170 in Erwinia tracheiphila SCR3

Name: gntU
Annotation: gluconate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details transmembrane" amino acids 26 to 47 (22 residues), see Phobius details amino acids 59 to 78 (20 residues), see Phobius details amino acids 103 to 132 (30 residues), see Phobius details amino acids 140 to 163 (24 residues), see Phobius details amino acids 175 to 198 (24 residues), see Phobius details amino acids 223 to 242 (20 residues), see Phobius details amino acids 262 to 283 (22 residues), see Phobius details amino acids 295 to 316 (22 residues), see Phobius details amino acids 329 to 351 (23 residues), see Phobius details amino acids 356 to 377 (22 residues), see Phobius details amino acids 383 to 408 (26 residues), see Phobius details amino acids 421 to 445 (25 residues), see Phobius details TIGR00791: transporter, gluconate:H+ symporter (GntP) family" amino acids 4 to 443 (440 residues), 548.7 bits, see alignment E=5.6e-169 PF02447: GntP_permease" amino acids 5 to 440 (436 residues), 528.4 bits, see alignment E=1.4e-162 PF03600: CitMHS" amino acids 18 to 390 (373 residues), 48.8 bits, see alignment E=5.8e-17

Best Hits

Swiss-Prot: 82% identical to GNTU_ECO57: Low-affinity gluconate transporter (gntU) from Escherichia coli O157:H7

KEGG orthology group: K06156, Gnt-I system low-affinity gluconate transporter (inferred from 91% identity to ebi:EbC_42260)

MetaCyc: 82% identical to low-affinity gluconate transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-209

Predicted SEED Role

"Low-affinity gluconate/H+ symporter GntU" in subsystem D-gluconate and ketogluconates metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (446 amino acids)

>LU632_RS19170 gluconate transporter (Erwinia tracheiphila SCR3)
MATLTLVLTAAGSVLLLLLLVMKARMHAFLALMLVSVGAGLFSGMPLDKIAETMQKGMGG
TLGFLAVVVALGAMFGKILHETGAVDQIAIKMLKAFGENRAHYAMGIAGLICALPLFFEV
AVVLLISIAFAVARRTNGNLVKLVIPLFAGVAASAAFLLPGPAPMLLASQMHVDFGWMIL
LGLCAAIPGMLIAGPLWGSFISRHVAFTLPAETSHPELDEHKLPSFAFSLSLILFPLILV
GLKTIGTRFTAQGSTLYEWLEFIGHPFIAILLACLVAIYGLAYRQGMDKERVMKICGSAL
QPAGIILLVIGAGGVFKQVLVDSGVGPALGNALTGSGLPVAVSCFILAGAVRIIQGSATV
ACLTTVGLIMPVIEPLHYSGAQMAALSICIGGGSIIISHVNDAGFWLFGRFTGATEGQTL
KTWTVMETILGTSGAIIGMVAFELLS