Protein Info for LU632_RS18225 in Erwinia tracheiphila SCR3

Annotation: metal ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 292 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF01297: ZnuA" amino acids 27 to 289 (263 residues), 258.4 bits, see alignment E=4e-81

Best Hits

Swiss-Prot: 32% identical to MNTA_LISMO: Manganese-binding lipoprotein MntA (mntA) from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)

KEGG orthology group: K02077, zinc/manganese transport system substrate-binding protein (inferred from 73% identity to pva:Pvag_0400)

Predicted SEED Role

"Zinc ABC transporter, periplasmic-binding protein ZnuA" in subsystem Transport of Zinc

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (292 amino acids)

>LU632_RS18225 metal ABC transporter substrate-binding protein (Erwinia tracheiphila SCR3)
MKMLPVTLAVAAFFVSPFVLANTVNTVASFSVLADIVKEVGGEHVKVKSLVGFDGDPHSF
EPTPQDSQVLLKADAVFVSGLGMEGWMDRLISASGYKGKVIVASQGITTRTMEDEGRIVT
DPHAWNSMKNGEVYATNVMNALIAIDPEDADYFRQRGLAYITELQKLDDWAKTEFAAVPA
EKRKVLTSHDAFGYFGQRYGVSFLSPAGFSTESEASASDVAGLITQLKKEHIHSYFIENQ
TDPRLVKQIASATGAKPGGELYPEALTKKDGMANSYIAAFRHNVNAMVESMK