Protein Info for LU632_RS17575 in Erwinia tracheiphila SCR3

Annotation: microcin C ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 338 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 140 to 165 (26 residues), see Phobius details amino acids 177 to 195 (19 residues), see Phobius details amino acids 201 to 220 (20 residues), see Phobius details amino acids 254 to 282 (29 residues), see Phobius details amino acids 303 to 325 (23 residues), see Phobius details PF12911: OppC_N" amino acids 9 to 42 (34 residues), 24.2 bits, see alignment 2.5e-09 PF00528: BPD_transp_1" amino acids 155 to 335 (181 residues), 102.5 bits, see alignment E=2.5e-33

Best Hits

Swiss-Prot: 82% identical to YEJE_ECOLI: Inner membrane ABC transporter permease protein YejE (yejE) from Escherichia coli (strain K12)

KEGG orthology group: K13895, microcin C transport system permease protein (inferred from 88% identity to ebi:EbC_30130)

MetaCyc: 82% identical to putative oligopeptide ABC transporter membrane subunit YejE (Escherichia coli K-12 substr. MG1655)
3.6.3.23-RXN [EC: 7.4.2.6]

Predicted SEED Role

"Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) (TC 3.A.1.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (338 amino acids)

>LU632_RS17575 microcin C ABC transporter permease (Erwinia tracheiphila SCR3)
MNPVNQARWARFCHNRRGYWSLWIFAVIFVLCLGAELLANDKPLLVSYQGQIRFPLLINY
SESDFGGPLTSAADYQDPWLKSRIEQQGWAIWAPVRFGDGTINFTSTVPFPSAPSVHNWL
GTDANGGDVLARLLYGTRISLLFGLMLTLISSAIGVVVGACQGYYGGRLDLWGQRLIEVW
SGMPTLFLIILLSSVIQPGFWWLLAITVLFGWMQLVGVVRAEFLRARNFDYIRAAQALGV
SDGKIMLRHMLPNAMVATLTYLPFILCGSITTLTSLDFLGFGLPLGSPSLGELLLQGKNN
LQAPWLGITAFLTLAIVLSLLIFIGEAVRDAFDPSKVY