Protein Info for LU632_RS15670 in Erwinia tracheiphila SCR3

Name: ffh
Annotation: signal recognition particle protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 TIGR00959: signal recognition particle protein" amino acids 2 to 429 (428 residues), 591.9 bits, see alignment E=3.5e-182 PF02881: SRP54_N" amino acids 5 to 82 (78 residues), 80.2 bits, see alignment E=3.1e-26 PF06414: Zeta_toxin" amino acids 95 to 206 (112 residues), 25.7 bits, see alignment E=2.1e-09 PF00448: SRP54" amino acids 100 to 296 (197 residues), 254.9 bits, see alignment E=1.5e-79 PF02492: cobW" amino acids 102 to 251 (150 residues), 21.9 bits, see alignment E=3.5e-08 PF01656: CbiA" amino acids 110 to 256 (147 residues), 27.8 bits, see alignment E=6.6e-10 PF02978: SRP_SPB" amino acids 329 to 427 (99 residues), 117.5 bits, see alignment E=8.8e-38

Best Hits

Swiss-Prot: 91% identical to SRP54_ECOLI: Signal recognition particle protein (ffh) from Escherichia coli (strain K12)

KEGG orthology group: K03106, signal recognition particle subunit SRP54 (inferred from 95% identity to epy:EpC_27840)

Predicted SEED Role

"Signal recognition particle, subunit Ffh SRP54 (TC 3.A.5.1.1)" in subsystem Two cell division clusters relating to chromosome partitioning or Universal GTPases (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (453 amino acids)

>LU632_RS15670 signal recognition particle protein (Erwinia tracheiphila SCR3)
MFDNLTDRLSQTLRNISGRGRLTEDNIKDTLREVRMALLEADVALPVVREFINRVKERAL
GQDVNKSLTPGQEFIKIVQNELVAAMGAENNTLNLAAQPPAVILMAGLQGAGKTTSVGKL
GKFLREKHKKKVLVVSADVYRPAAIKQLEKLAEQVGVDFCPSDLSQQPVYIVKNALQQAK
LKFYDVLLVDTAGRLHVDEAMMDEIKQVHAVINPVETLFVVDAMTGQDAANTAKAFNEAL
PLTGVILTKVDGDARGGAALSIRHITDRPIKFMGVGEKTDALEPFYPDRIASRILGMGDV
LSLIEDIESKVDRVQAEKLASKLKKGDGFDLNDFLQQLKQMRNMGGMASLMGKLPGMGQL
PDNVKSQMDDKVLVRMEAMINSMTRKEREKPEIIKGSRKRRVATGSGMQVQDVNRLLKQF
DDMQRMMKKMKKGGMAKMMRGMKGMMPPGFPGR