Protein Info for LU632_RS15275 in Erwinia tracheiphila SCR3

Annotation: co-chaperone YbbN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 PF00085: Thioredoxin" amino acids 8 to 107 (100 residues), 70.2 bits, see alignment E=2.7e-23 PF13728: TraF" amino acids 9 to 88 (80 residues), 27 bits, see alignment E=7.5e-10 PF14559: TPR_19" amino acids 125 to 191 (67 residues), 59.4 bits, see alignment E=7e-20 PF14561: TPR_20" amino acids 196 to 285 (90 residues), 100.2 bits, see alignment E=1.3e-32

Best Hits

Swiss-Prot: 76% identical to CNOX_ECOLI: Chaperedoxin (cnoX) from Escherichia coli (strain K12)

KEGG orthology group: K05838, putative thioredoxin (inferred from 86% identity to ebi:EbC_10750)

Predicted SEED Role

"FIG000875: Thioredoxin domain-containing protein EC-YbbN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (285 amino acids)

>LU632_RS15275 co-chaperone YbbN (Erwinia tracheiphila SCR3)
MSSQAAIISINESNLHQTLEQSMQVPVLFYFWSARSQHCQELTPLLERLAQEYAGQFVLA
ELDCDAEPAVAQQFGLRSIPTVYLFQNGQPVDGFQGPQPEEAIRTLLHKVLPKEEELKAQ
QGMQLMQEGKMLEALPLLKEAWQLSKQSSEMGFLLAEALITLNRSDEAQAVLDVVPLQDK
DTRYHGLIAQIDLLKQAADTPEIQQLQQQIDADPDNAELATKLALQLHQVGRNEEALALL
FGFLKNDLSAADGQARKILQEILAALGTGDALASQYRRKLYALLY