Protein Info for LU632_RS14765 in Erwinia tracheiphila SCR3

Name: lpoB
Annotation: penicillin-binding protein activator LpoB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 188 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details TIGR02722: uncharacterized lipoprotein" amino acids 2 to 187 (186 residues), 153.9 bits, see alignment E=2.6e-49 PF13036: LpoB" amino acids 49 to 185 (137 residues), 111.4 bits, see alignment E=1.9e-36

Best Hits

Swiss-Prot: 69% identical to LPOB_ERWAC: Penicillin-binding protein activator LpoB (lpoB) from Erwinia amylovora (strain CFBP1430)

KEGG orthology group: K07337, hypothetical protein (inferred from 75% identity to ebi:EbC_16660)

Predicted SEED Role

"Lipoprotein YcfM, part of a salvage pathway of unknown substrate"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (188 amino acids)

>LU632_RS14765 penicillin-binding protein activator LpoB (Erwinia tracheiphila SCR3)
MLLTLVLTGCISQQQGQQPAKTTESEPVQPVQNPVAPPAHPAQTLPQPPKMQSINWDASV
TPLVAQMLKAQGITPGSVLLVDGVKNSTNGSLQRSKATDALNNALQNNTEFTLVKPEQLA
AAKQTLGLSASDSLGSRSKAVGLARYLGAQYVLYTNVRGDVKSPTLQMQLMLVQTGELIW
SGDGAVQF