Protein Info for LU632_RS12470 in Erwinia tracheiphila SCR3

Annotation: DUF441 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 148 signal peptide" amino acids 1 to 8 (8 residues), see Phobius details transmembrane" amino acids 9 to 32 (24 residues), see Phobius details amino acids 51 to 73 (23 residues), see Phobius details amino acids 81 to 102 (22 residues), see Phobius details amino acids 112 to 145 (34 residues), see Phobius details PF04284: DUF441" amino acids 8 to 145 (138 residues), 150.4 bits, see alignment E=1.7e-48

Best Hits

Swiss-Prot: 84% identical to Y1746_ERWT9: UPF0756 membrane protein ETA_17460 (ETA_17460) from Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)

KEGG orthology group: None (inferred from 93% identity to ebi:EbC_22670)

Predicted SEED Role

"Putative inner membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (148 amino acids)

>LU632_RS12470 DUF441 domain-containing protein (Erwinia tracheiphila SCR3)
MFDLTLFILLLLVGLSYFSHNLTVAIALLVLIIIRMTPLNTFFPWIEKQGVTVGIIILTI
GVMAPIASGTLSGSTLMHSFLHWKSLLAIAIGIFVSWVGGRGVSLMSAQPSVVGGLLIGT
IIGVSLFRGVPVGPLIAAGLVSLFIGKM