Protein Info for LU632_RS09975 in Erwinia tracheiphila SCR3

Name: pqiA
Annotation: membrane integrity-associated transporter subunit PqiA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 424 transmembrane" amino acids 53 to 78 (26 residues), see Phobius details amino acids 99 to 123 (25 residues), see Phobius details amino acids 144 to 163 (20 residues), see Phobius details amino acids 170 to 188 (19 residues), see Phobius details amino acids 255 to 276 (22 residues), see Phobius details amino acids 302 to 328 (27 residues), see Phobius details amino acids 349 to 372 (24 residues), see Phobius details amino acids 379 to 402 (24 residues), see Phobius details TIGR00155: integral membrane protein, PqiA family" amino acids 1 to 410 (410 residues), 511.7 bits, see alignment E=7.5e-158 PF04403: PqiA" amino acids 49 to 200 (152 residues), 129.2 bits, see alignment E=6.2e-42 amino acids 253 to 411 (159 residues), 184.4 bits, see alignment E=6.7e-59

Best Hits

Swiss-Prot: 69% identical to PQIA_SHIFL: Intermembrane transport protein PqiA (pqiA) from Shigella flexneri

KEGG orthology group: K03808, paraquat-inducible protein A (inferred from 77% identity to ebi:EbC_15350)

Predicted SEED Role

"Paraquat-inducible protein A" in subsystem Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (424 amino acids)

>LU632_RS09975 membrane integrity-associated transporter subunit PqiA (Erwinia tracheiphila SCR3)
MCSSHHADSWMLCPQCDLMSQLPELQPGNKANCPRCGTILLANWHEPQNRPTAYALAALV
MLVLANLFPFVSMSVAGLSSEITLMRIPQVMASENYSSLATLFMLFVQAVPAICMVAILL
LVNPVSLPSPVKQLMAKMLFQMKSWGMAEIFLAGVLVSFVKLMAYGDIGIGTSFVPWCFF
CLLQIRVFQCIDRRSLWARISPLPPLSSSPLPAVSGIRQGLRSCSCCTAVLPAEQFICPR
CATGGYVRRRHSLQWTLALLLTSLLLYIPANLFPVMVTEALGSKITSTIMAGVILIWSEG
SWPVALIIFIASIMVPSLKMLAISWLCWDASGSGKKHYGSDKMHKIYEVVEFVGRWSMID
VFVIAILSALVRMGRLMSIYPAPGALLFALVVILTMFAAMTFDPRLCWDRVSEKSPEEPS
IEGK