Protein Info for LU632_RS09725 in Erwinia tracheiphila SCR3

Name: cydD
Annotation: cysteine/glutathione ABC transporter permease/ATP-binding protein CydD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 586 transmembrane" amino acids 23 to 45 (23 residues), see Phobius details amino acids 63 to 82 (20 residues), see Phobius details amino acids 140 to 159 (20 residues), see Phobius details amino acids 165 to 188 (24 residues), see Phobius details amino acids 245 to 269 (25 residues), see Phobius details amino acids 281 to 302 (22 residues), see Phobius details TIGR02857: thiol reductant ABC exporter, CydD subunit" amino acids 22 to 556 (535 residues), 595.4 bits, see alignment E=6.3e-183 PF00664: ABC_membrane" amino acids 29 to 292 (264 residues), 123.3 bits, see alignment E=1.6e-39 PF00005: ABC_tran" amino acids 370 to 514 (145 residues), 103.2 bits, see alignment E=1.9e-33

Best Hits

Swiss-Prot: 62% identical to CYDD_ECOLI: ATP-binding/permease protein CydD (cydD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 69% identity to ebi:EbC_14880)

MetaCyc: 62% identical to glutathione/L-cysteine ABC exporter subunit CydD (Escherichia coli K-12 substr. MG1655)
7.4.2.-; 3.6.3.M9 [EC: 3.6.3.M9]

Predicted SEED Role

"Transport ATP-binding protein CydD" in subsystem Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.M9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (586 amino acids)

>LU632_RS09725 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD (Erwinia tracheiphila SCR3)
MNKSRQQQLLRWLKCQSVHGKGWLRLSQLLGIFSALFILAQAWLMADMFQSLIVDNLPRE
NLFSQFIMLIGCFFLRALLVWLREKAGFEYGNVIRKNLRENVLNRLEVLGPAWIQGKPAG
TWATLLLEQIEDMQDYFARYLPQMLLATLIPCLILLILLPINWVAAVILFVTAPLIPLFM
ALAGMGAADANQRNFKALARLSGHFLDRLRGLDTLRLFYRAEKETQDIRMASTNFRQHTM
AVLRLAFLSSAVLEFFASLSIAVVAVYFGFSYLGELNFGHYGHGVTLFAGFLALILAPEF
FLPLRELGTFYHAKAQAIGGADALEAFLTETAEIPAERGEQEPDFSHEFNVVAEGLRILS
PHNTLLAGPLNFTLSAGKRVVLIGQSGAGKTSLLNVLLGNLPYQGSLRINGVELRDVRQK
YWHQHLAWVGQNPHLPANTLAENIAPDGSRDLARLQQICDTAAVTEFIPHLPDGLASEIG
EQADKLSVGQTQRVAVARALYKSCKMLLLDEPTASLDSRSEYHVNKALIAASYQHTTLLV
THHLHLLHLWDEIWLMHEGRLVQQGNVEQLSQEGGLFAQLISRDRG