Protein Info for LU632_RS09290 in Erwinia tracheiphila SCR3

Annotation: amino acid adenylation domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1284 transmembrane" amino acids 1156 to 1174 (19 residues), see Phobius details PF00501: AMP-binding" amino acids 36 to 382 (347 residues), 265.3 bits, see alignment E=2e-82 TIGR01733: amino acid adenylation domain" amino acids 51 to 458 (408 residues), 369.3 bits, see alignment E=1.2e-114 PF00550: PP-binding" amino acids 948 to 1010 (63 residues), 45.9 bits, see alignment 1.3e-15 PF00975: Thioesterase" amino acids 1033 to 1146 (114 residues), 92.1 bits, see alignment E=1.6e-29 PF00561: Abhydrolase_1" amino acids 1034 to 1156 (123 residues), 29.3 bits, see alignment E=1.7e-10

Best Hits

Predicted SEED Role

"Peptide synthetase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1284 amino acids)

>LU632_RS09290 amino acid adenylation domain-containing protein (Erwinia tracheiphila SCR3)
MTFIHHAACSVASSYEPGLHDKLHDILAMLSDHALSIPEQTAVKDESTSLTYRDFQQRVS
RDAASLGALIDETVQFIGLWCDPSVDMVCGAWSILAAGRAYLPLAPEYPAERIRYMIEDS
GVTVLLTQQHLKAQLMAIVDKSITVLTQSDLQQVRPALCPRTPDHNQARLAYMIYTSGST
GKPKGVMVTWHNISSQMAWLKDRFGFDYRDTLLQKTPVSFDAAQWEILAPALGCGMMVGP
KNCYRDADAMIEIVQKHSITILQCVPTLLQALVEHPLFPDCVTLKQVFSGGEILTRRLAE
EFFQRLPEARLTNLYGPTECTINASSFTLDALDVSSYPDAIAIGHPVADTRYHVLNSAHE
PVKPGETGELYISGAQVARGYWRRPDLTREKFISASGRIIPGHERLYRTGDLVRQDTAGN
TWFVSRADNQIKLRGYRVELDEIRLAIEKHHWVQNAAVIVQDATCSGFQVLIACIELDKR
QAALMDQGNHDRHHITKANKLQVKAQLSNAGCRQLSARQEAESIALPFKTPERKHWEAAF
GRKTYRFFEGDPHIKRETLIKVLQRRPDAVSTPDALNLDNLGKLLRYFGQFISEDRLLPK
YTYASPGALYATQLYLELDGIAGLPGAVYYYHPVAHSLVPIAPLSGTSAPWIKLHFIGDR
DAIEPVYKNNLREVLEMETGHMLGLFDELLPAFGLYAERSASQRGALPLWYDGKQDNDYL
GGYLVSTSPAKPDAASIQTWLQLHCPVDRLDPGLYLFQHGALHYITERMLQKKDVIAINQ
RVFERAQFGIGVVCNGADPEEHYVLAGREMHRLQNNDHLLGMMPSGYSSKSNHDLPAATE
MRKILAQFNMPMDCFYFCIGGPVSKAQYLHKGMNEDRIHMQGPVELLKEDLANQLPSYMI
PNNVVILDRLPQTANGKIDSLALKALPELNQTEGNSEKIALKTNVEKTIGEIWCSVMKWQ
QVWATEDFFASGGNSLTAVALINRINKTFAIRLPLQTIFQTPTVSGLASAVEKYGQHSAA
CSRIINLNGFTQRPVFCWPGLGGYPLNLRELAEKLPDQRAFFGIQSLGINEGETPLATIT
HMAQEDIAQIKTVQPDGPYTLWGYSFGARVAFEAAAQLEAQGETVEALCLLAPGAPITQI
EREQRYSHRATFDNPVFVAILFSVFAHQIGGELLERCLAKCKSREAFIAFICQRFPLLHV
DVVARIIHIVETTYKFSYTFDELKDRQISAPITIVKAQGDNYSFLDNAPVFSKQKPALIE
LDTDHFRLLKPDGINELLQKLLLP