Protein Info for LU632_RS07930 in Erwinia tracheiphila SCR3

Annotation: DUF412 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 transmembrane" amino acids 46 to 64 (19 residues), see Phobius details amino acids 70 to 89 (20 residues), see Phobius details PF04217: DUF412" amino acids 10 to 148 (139 residues), 190.7 bits, see alignment E=6.2e-61

Best Hits

Swiss-Prot: 77% identical to Y3315_SERP5: UPF0208 membrane protein Spro_3315 (Spro_3315) from Serratia proteamaculans (strain 568)

KEGG orthology group: K09899, hypothetical protein (inferred from 82% identity to eta:ETA_11950)

Predicted SEED Role

"FIG00638298: membrane protein YfbV"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (150 amino acids)

>LU632_RS07930 DUF412 domain-containing protein (Erwinia tracheiphila SCR3)
MANESGSDGWFKLFRHGQHYMKTWPADKRLAPVFPENRVMKTTRFAIRYMPPLAVFVMTW
QIALGGQPGPAVTTALFACSLPVQGLWWLGKRSVTPLPPALLNWFNTVRDKLLASGMALA
PVEGKPTYQSLADVLKRAFKQLDRTFLDDL