Protein Info for LU632_RS05845 in Erwinia tracheiphila SCR3

Annotation: LysR family transcriptional regulator ArgP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 TIGR03298: transcriptional regulator, ArgP family" amino acids 5 to 293 (289 residues), 371.5 bits, see alignment E=1.3e-115 PF00126: HTH_1" amino acids 7 to 64 (58 residues), 68.6 bits, see alignment E=3.6e-23 PF03466: LysR_substrate" amino acids 93 to 287 (195 residues), 55.5 bits, see alignment E=5.3e-19

Best Hits

Swiss-Prot: 96% identical to ARGP_ERWT9: HTH-type transcriptional regulator ArgP (argP) from Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)

KEGG orthology group: K05596, LysR family transcriptional regulator, chromosome initiation inhibitor (inferred from 97% identity to ebi:EbC_36520)

Predicted SEED Role

"Chromosome initiation inhibitor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (298 amino acids)

>LU632_RS05845 LysR family transcriptional regulator ArgP (Erwinia tracheiphila SCR3)
MKRPDYRTLQALDAVVRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPT
EQGQKLLALLHQVELLEEEWLGDENGGTTPLLLSIAVNADSLATWLLPALKTVLSDSPVR
LNLQVEDESRTQERLRRGEVVGAVSIQPQPLPSCLVDQLGALDYLFVGSKEFAARYFQNG
VTRSALLKAPAVAFDHLDDMHQAFLQQNFDLSPGSVPCHIVNSSEAFVQLARQGTTCCMI
PHLQIERELAEGELIDLTPGLFQRRMLYWHRFTPESRLMRKVTDALIAYGHRVLRQAL