Protein Info for LU632_RS02840 in Erwinia tracheiphila SCR3

Name: sgrR
Annotation: HTH-type transcriptional regulator SgrR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 553 transmembrane" amino acids 455 to 474 (20 residues), see Phobius details PF12793: SgrR_N" amino acids 5 to 118 (114 residues), 134.9 bits, see alignment E=1.5e-43 PF00496: SBP_bac_5" amino acids 164 to 306 (143 residues), 63.6 bits, see alignment E=1.8e-21

Best Hits

Swiss-Prot: 68% identical to SGRR_YERPS: HTH-type transcriptional regulator SgrR (sgrR) from Yersinia pseudotuberculosis serotype I (strain IP32953)

KEGG orthology group: K11925, SgrR family transcriptional regulator (inferred from 79% identity to ebi:EbC_07020)

Predicted SEED Role

"SgrR, sugar-phosphate stress, transcriptional activator of SgrS small RNA" in subsystem Sugar-phosphate stress regulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (553 amino acids)

>LU632_RS02840 HTH-type transcriptional regulator SgrR (Erwinia tracheiphila SCR3)
MSSPRLKQQFIRLWQSCEGQSQQTTLNDLALRLNCSRRHMRSLLNAMQQQGWLEWHAEAG
RSKRSQLNFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKNAVRQMLVSRLGRSFRQGKH
ILRILYYRSLLNLLPGTPLRRSETHLARQIFSGLTRINEENGEIEADIAHHWQQITPLHW
RFFLRPAIHFHHGRELEMADVIATLERLTSQPLYANLHKISSSSPWSLDIYLHQPDHWLP
WLLGSVSSMILPKEWPSIANFARQPIGTGPYQVVRNQQRQLRIEAFDDYFGYRALIDEVN
IWVLPEISEELVYASVRLQSDSLSDKSEESRLEEGCYFLLFDQRSERGRNEQVRRWVNSL
CNPVALLNQADIGYQRYWFPAYGLLPRWHHQRDLTRSTKPAGLTSLTLTWYDDHIEYQAI
ANTLEPLLAAGGVTLVTRQVDYATWHRGDAESDIWLGSANFTLPLAFSLFALLYEIPLVH
HCVATNWETDVQKWRENNLTLTEWSKRIIDSHTLHPLFHHWLLLEGIRTMRDVKMNTLGW
FDFKSAWFAPPEG