Protein Info for LU632_RS02190 in Erwinia tracheiphila SCR3

Annotation: DgaE family pyridoxal phosphate-dependent ammonia lyase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01437: uncharacterized pyridoxal phosphate-dependent enzyme
  • amino acids 4 to 366 (363 residues), 581.5 bits, E=3e-179
• PF03841: SelA
  • amino acids 56 to 268 (213 residues), 48.2 bits, E=8.6e-17

Best Hits

KEGG orthology group: K01042, L-seryl-tRNA(Ser) seleniumtransferase [EC: 2.9.1.1] (inferred from 91% identity to ebi:EbC_04910)

Predicted SEED Role

"D-Glucosaminate-6-phosphate ammonia-lyase (EC 4.3.1.-)" (EC 4.3.1.-)

MetaCyc Pathways

• L-selenocysteine biosynthesis I (bacteria) (2/3 steps found)

KEGG Metabolic Maps

• Aminoacyl-tRNA biosynthesis
• Selenoamino acid metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.9.1.1 or 4.3.1.-

Protein Sequence (373 amino acids)

>LU632_RS02190 DgaE family pyridoxal phosphate-dependent ammonia lyase (Erwinia tracheiphila SCR3)
MSSIYEKYGLKQVINASGRMTILGVSTPAADVVDTVKYGLNHYFEIKDLVNKTGAYIASL
LGCEDAVVVACASAGIAQSVAAVIVKDDDWLLENLHAAPLVVPHDIVVPKGHNVNFGAPV
GTMVAMGGGRLIEAGYANECSADQLSAAVTPQTAAILYIKSHHCVQKSHLSVEQAAVVAR
KHGVPLIVDAAAEEDLQCYYQDGADLVIYSGAKAIEGPTSGLVMGRKQYVEWVKRQSMGI
GRAMKVGKEGILGLTQAIENYLVQEKVSGAQMVEKMTPFIDNLNALNGISARVVWDAAGR
DIARAEIHFDEAVIGHTTGDVVQVLKTGEIAIYFRGYKANEGIVEVDVRSLTADQLNTIF
VCIKALLSGGKNA