Protein Info for LU632_RS00450 in Erwinia tracheiphila SCR3

Name: sctC
Annotation: type III secretion system outer membrane ring subunit SctC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 590 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF21304: T3S_SPI-1_N0" amino acids 53 to 121 (69 residues), 111.7 bits, see alignment E=2.3e-36 PF03958: Secretin_N" amino acids 128 to 185 (58 residues), 28.4 bits, see alignment 2.3e-10 amino acids 199 to 330 (132 residues), 44.9 bits, see alignment E=1.6e-15 TIGR02516: type III secretion outer membrane pore, YscC/HrcC family" amino acids 284 to 545 (262 residues), 277.3 bits, see alignment E=1e-86 PF00263: Secretin" amino acids 386 to 545 (160 residues), 98.9 bits, see alignment E=3.8e-32

Best Hits

KEGG orthology group: K03219, type III secretion protein SctC (inferred from 68% identity to eam:EAMY_0777)

Predicted SEED Role

"Type III secretion outermembrane pore forming protein (YscC,MxiD,HrcC, InvG)" in subsystem Type III secretion systems, extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (590 amino acids)

>LU632_RS00450 type III secretion system outer membrane ring subunit SctC (Erwinia tracheiphila SCR3)
MNRNFFKKLFHLIVLLSAVLNCNYAAARLLNTPDNETNQYRSSDHPNRSEDIYVASDNNV
KQFFYVLGSALNKPVIVSNEAAKKRISGNFDLSHPDELLKTVAIRTGLIWYDDGSSIYVY
DSNEVQSSVVKLSFAPYDRLVAFLRSSGLYDNRFPLRSDGQSGSFYVSGPPVYVELVSAA
AKYIDTTYSRTETGEVSIRVIKLKNTFVNDRTYIQRDTPVTIAGVATVLNKLLNNLRVGV
PIGAAKITVDNDTQRAMQAATADQTGLYPQLPLFNSAPSQSAYSDASSSREDTVNIVAYS
DTNSLLIQGSPRQVSFVEDLVQAMDIAKQQIQLSLWIIDISKDQVDKLGVRWEGALTLGN
TGVTVNSSTLTPSNSAHFLADVNAQVQRGNAQIVSRPEILTQENVPALFDNNTSFYTKLV
GERTASLEKVTYGTMISVLPRLTQDRREIEMILNIQDGGTPLGSNGQTAFVDNLPIVNNT
QISTEARVPAGYGLLVGGYSRDEDTRHNVGVPLLRDIPLLGRAFDYNYVTRKKMVRMFLI
QPRLLTSGETWQGRSNDNPVLGYGSAQEALTLKSTVSMLRDNMKNSDGNE