Protein Info for LU632_RS00440 in Erwinia tracheiphila SCR3

Annotation: PrgH/EprH family type III secretion apparatus protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 417 transmembrane" amino acids 167 to 188 (22 residues), see Phobius details TIGR02554: type III secretion apparatus protein PrgH/EprH" amino acids 20 to 412 (393 residues), 191.5 bits, see alignment E=1.3e-60 PF09480: PrgH" amino acids 23 to 411 (389 residues), 219.6 bits, see alignment E=4.3e-69

Best Hits

KEGG orthology group: None (inferred from 51% identity to eay:EAM_2669)

Predicted SEED Role

"Pathogenicity 1 island effector protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (417 amino acids)

>LU632_RS00440 PrgH/EprH family type III secretion apparatus protein (Erwinia tracheiphila SCR3)
MNSDQIKNVSADYSEEPAQIYCLKVLFGPMLGCELHLPEGDYFLIIEPGLALQDKTNNIT
SEQQHAAHYTLNTLYIPCDKPSPNIILRLSNSLEEGGFRLELQDSAGFSTDIIEENKIFS
HEHIHLALKRHDADWEEAITHFNLLPAKSKAEHEDNLQHRIKKRKELIFLIAFLLLAVLF
IGTGILWYKKTEYNQQVLTLTEVLSGAPAPLQVVKGRDGKKIYVLAHNLPEMEWSTQAIR
KMNESHRVIPIWLRQHGQDTIRRLFQAGYPVLQLDFNSPSHPVISLYRDPLPVEEKKLKS
ALLEYLPFYDDISITIKTKSQLLAEARQGLDRLHVPYRKIDTANGYALVVKDALSDSVLF
ALRDFIVEFNRKWGSNVINFSINLDENWLQNKSYVDSPDGYLFLNPRHWYFPLNKVR