Protein Info for LRK53_RS17725 in Rhodanobacter sp000427505 FW510-R12

Annotation: substrate-binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF12849: PBP_like_2" amino acids 33 to 268 (236 residues), 83 bits, see alignment E=3.3e-27 PF01476: LysM" amino acids 402 to 443 (42 residues), 53.4 bits, see alignment 1.9e-18

Best Hits

Predicted SEED Role

"Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism (TC 3.A.1.7.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (446 amino acids)

>LRK53_RS17725 substrate-binding domain-containing protein (Rhodanobacter sp000427505 FW510-R12)
MSVRLARLLSVALIGACLATPAFAKSKSKAQHASTPAKSSLVWRGDVATANGVVNEVAKA
WEKSGHGRIELQPFNTASGIDAVASGAADLAGSARASDNSAQNANLTFTPVAWDALVIVT
QSSNPVRSLSLKQVHDIYYGRIHNWSEVGGSNAPIDVYAVASPGDGVEYSLRELLFGRGN
QPVAAPRLYVNTRKLEEGIALNPNGLGVSTLASISGNPKLKAIPIDGKPATAANIADGSY
PLFIPLYLVTNPRSPKAAQAQAFIDFMQTAPAEATLRKHAVLPYQDGAALVALDTSRRSR
ILAEAGARPVRGTPLSAPGATYAARAAIAPTSPDTLAARQAVERRRAEAQDNARLSRIQG
SVSDVTVTGVDHASGSATSFDRSVGKDFGKVDANASHALTTYKVAKGDTLSTIAKRHSVE
VAQLRQWNHLKNDQLKLGQVLRLRDR