Protein Info for LRK53_RS17640 in Rhodanobacter sp000427505 FW510-R12

Annotation: Atxe2 family lasso peptide isopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 745 signal peptide" amino acids 1 to 51 (51 residues), see Phobius details PF07676: PD40" amino acids 65 to 83 (19 residues), 19.4 bits, see alignment (E = 8.4e-08) PF00326: Peptidase_S9" amino acids 554 to 710 (157 residues), 34 bits, see alignment E=2.2e-12

Best Hits

Predicted SEED Role

"acylaminoacyl-peptidase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (745 amino acids)

>LRK53_RS17640 Atxe2 family lasso peptide isopeptidase (Rhodanobacter sp000427505 FW510-R12)
MKLFRQPAPCVAAMVRMRVYASKTRKRPVHWASVLAFAVLGMAVVGSLHAETIPPRRLLE
VTDLGNPAISPDGRYVAFRSERASVERNTYDTTWYVQGVDGKAPPLRVADGGMPLLQYVN
GTVLPSPAVWPPDGKWIYYRALFNGRVAVWRAAADGSGARAVTADPADVRDFTLSRDGRK
LMYSVGATREEVIAAEDSEYDRGIRIDDTVNIDDGLFRQSVLNGRPTTRRYLAIPGVEGW
TAIGPLLEEVPDRWKAVDLATMTTRDLLTSEHPALRLTPADLSPDLPVAPVKIWNALRPQ
RYQITQHPDDGRIAVLLPGHKDKGLFESRYVELTMLADRHASQPIYCTAELCRHKNITDI
QWRSGSDEVLFTIADYGMGHAQFIYGWNVVTGKVRPIVLSQGLVSGSQRFWDIPCALSSD
TLVCVAAEADHPPRLEAIDVKSGRRRILFAPNKGLDADIAATVPAKPIRWKDAQGREFTG
QLFEVRGASAGHPPPLFVTFYTCEGFLRGGKGDEWPLTTLAEDGISALCINELPGANLDA
VANDNQGPAAVESVVKRLSAEGRIDRTRVGMGGLSHGSEVTMWTLAHSDVVSAASVSSGL
VTPTYYLFNSLRDSFRSSFRKFWQLGTPNETPERWKEISPAYQFDRIKAPILFQVPEKEY
LDTLDYAIPLMRRHQADMYVFPYETHIKYQPRHKLAVYERNVDWFRFWLQGYEDPSPEKA
GQYRIWREMEKAAKHHFGVSAHDGP