Protein Info for LRK53_RS16945 in Rhodanobacter sp000427505 FW510-R12

Annotation: serine/threonine-protein kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1099 transmembrane" amino acids 298 to 318 (21 residues), see Phobius details PF07714: PK_Tyr_Ser-Thr" amino acids 28 to 272 (245 residues), 98.3 bits, see alignment E=1.9e-31 PF00069: Pkinase" amino acids 28 to 273 (246 residues), 157.9 bits, see alignment E=1.3e-49 PF13424: TPR_12" amino acids 651 to 721 (71 residues), 36.1 bits, see alignment 2.4e-12 amino acids 731 to 797 (67 residues), 41.4 bits, see alignment 5.3e-14 PF14938: SNAP" amino acids 668 to 802 (135 residues), 26.1 bits, see alignment E=2.3e-09 PF13374: TPR_10" amino acids 816 to 842 (27 residues), 14.9 bits, see alignment (E = 8.9e-06)

Best Hits

Predicted SEED Role

"serine/threonine protein kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1099 amino acids)

>LRK53_RS16945 serine/threonine-protein kinase (Rhodanobacter sp000427505 FW510-R12)
MTSEPTATGIYAHMNLAPGTMLAGRFRIEALLGVGGMGVVYRAHDTALDVPVALKLLRPE
LAARPDAFERFRQELLLARQVSSPQVVRIHDLAQHDGHWLISMDYVDGEGLDRRIDRGAL
PLEDALRITRQIALGLQAAHARQVVHRDLKPANVLIDREGNAYISDFGVARSLASSGLTL
AGTGAVIGTPDYLSPEQARGDPVDTRSDLYALGLILREMLTGTPAFQGATAAEAIAQRLV
RTPSPVTRERPDVPTWVARLIEQLLRPRPAHRLPDAAAVIEAIDRRAMPPDLRAHRRAWL
ATAALLTTIGVAGTLWWMPHDKAAGIAAAPPLHRVLVLPLRGAALPAPRVTALDAYLRAT
LFALPGVASVDADRTLQALRQLDAAGSAPDPATLRRLAVADRTLSPDLRQRDGHWYVHAE
LRGDDGVPQTVDGPLAADTVGALHAWLTEPALAKALGAPAPASELKLPTAIATLDTFGAV
LQAREKNDIPAALTDLRALTRHERDDPELWRTQLRLAQAIGERDVALEAIEHGQRAANAG
PARLQRVFAAERALSDGDVPAAITQWRAQLAETPDDTLADLQLARAQGGGGDFRAAIARL
SQLTARDSDDPRAWFELGKFSILQGEARRAVDDYLVRALVLYKRGRNLYGVAETTNALGI
GYGRLGQTANAEEQYRKAAALQRDVGNRRGVATSLRNLANVLSLRGAFDEAGSALAQARA
LTVELDDREGLAAVDNELGVLAEERGDYHAALDAYRRALQGWQQVGDAHGLAQALNDIGF
ANFQLGRYDDAQSYWQRTAESEAGLGDTGRIRTGQNLGLLAAARGRWPEARKLQEGALAE
AEKQQMPEEAAVSRRNLAKLALMQGDVAGSLAQADKAIALFSQRGDRRGEADTRLLRVQA
LLAAGAEAMARGELKALEGTGPGTSREQRAGVEIVRAQLAVHAGDPRSAAAALDDAQPLA
EASGVRELQLRVALLRAHLDPRADTGLDAATAMLGNAELRLDWLTLAMQRALAALDATAA
VRAYREAVNLMRGSEVLGAPQIHTLGASAQRLAGDGAGATAAEQAAAAARAAFQATLPDR
LHDAGSAPARRTEADAPMP