Protein Info for LRK53_RS16905 in Rhodanobacter sp000427505 FW510-R12

Annotation: chloride channel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 656 transmembrane" amino acids 49 to 71 (23 residues), see Phobius details amino acids 108 to 127 (20 residues), see Phobius details amino acids 205 to 230 (26 residues), see Phobius details amino acids 241 to 260 (20 residues), see Phobius details amino acids 275 to 295 (21 residues), see Phobius details amino acids 314 to 331 (18 residues), see Phobius details amino acids 351 to 372 (22 residues), see Phobius details amino acids 380 to 402 (23 residues), see Phobius details amino acids 411 to 436 (26 residues), see Phobius details amino acids 445 to 465 (21 residues), see Phobius details PF00654: Voltage_CLC" amino acids 119 to 459 (341 residues), 275.1 bits, see alignment E=9.4e-86 PF00571: CBS" amino acids 493 to 549 (57 residues), 27.5 bits, see alignment 3.2e-10 amino acids 559 to 613 (55 residues), 48.2 bits, see alignment 1.1e-16

Best Hits

KEGG orthology group: None (inferred from 60% identity to scl:sce0443)

Predicted SEED Role

"Chloride channel protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (656 amino acids)

>LRK53_RS16905 chloride channel protein (Rhodanobacter sp000427505 FW510-R12)
MTRATDTPVAHTDVRTVGSTDALPIAPALGLSLDAARMPRKSTLVTRRILLISVLAVILG
VLAAYIAQLLMLTINLITDLCFYGRVSDVIGPHARGGSFVLSPAGNQLGAWVILVPVIGG
LLAGIMARWGSRAIQGHGIPEAMEQILTNESNIPARITWLKPLSSAFAIGTGGPFGAEGP
IISTGGAMGSLIGQLLRVTANERKVLLAAGAAAGMAAVFGAPVASLVLAVELLLFELRPR
SLIPVALAAVTAVGVRYATYGAEPVFPMPVVPQPGGWALIGFVLIGGLVGYASVWVTKAV
YGVEDLFEKLPIHWMWWPALGALVAGVVGWIEPRTLGVGYDNIDALVQGHFGLAMLLSFG
ALKFISWVIALGSGTSGGTLAPLFMIGGSLGAVIGIGLDHVLPALAIDPRIAALVGMAAI
FAGSSRALLTAVVFAFETTHQPACLLPLLGGCTAAYLISALIMRNTIMTEKIARRGVRVP
SEYAADYLEQVAVGDVCSREVVTLRTSQTLAEVRPWLNDGAPETRHQGFPVVDESGRVYG
VLTRRTLLDPQWHYTQTLGELVTREPIAVNENHSLREAADHMVAEKVGRLIVVGKDDSRR
LVGILTRGDILAAHARRLREARESSRHLRFRDGLKPRQAAGDLMEGYGHARGSKKR