Protein Info for LRK53_RS16450 in Rhodanobacter sp000427505 FW510-R12

Annotation: methyltransferase domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 277 PF13847: Methyltransf_31" amino acids 43 to 151 (109 residues), 58.2 bits, see alignment E=2.3e-19 PF01209: Ubie_methyltran" amino acids 44 to 153 (110 residues), 30.2 bits, see alignment E=9e-11 PF13489: Methyltransf_23" amino acids 45 to 201 (157 residues), 54.2 bits, see alignment E=4.6e-18 PF08242: Methyltransf_12" amino acids 48 to 144 (97 residues), 66.7 bits, see alignment E=7.5e-22 PF13649: Methyltransf_25" amino acids 48 to 142 (95 residues), 73 bits, see alignment E=7.9e-24 PF08241: Methyltransf_11" amino acids 48 to 147 (100 residues), 82.7 bits, see alignment E=7.4e-27

Best Hits

KEGG orthology group: None (inferred from 72% identity to sml:Smlt0786)

Predicted SEED Role

"Methyltransferase (EC 2.1.1.-)" (EC 2.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (277 amino acids)

>LRK53_RS16450 methyltransferase domain-containing protein (Rhodanobacter sp000427505 FW510-R12)
MNSSTTAGEFPYIHGFSAEEQSRLVRQAHMFETSLFSHIDYSDATRLLEVGCGVGAQTEI
LLRRFPQLHVTGIDRSAAQLAAASHNLGQTPWCATRYTLQQADATDLPFAERSFDAAYLC
WVLEHMPSPARVLSEVRRVLSPSATVYVTEVLNSSFFLDPYSPNLLRYWMAFNDYQYDSG
GDPFIGAKLGNLLLAGGYRDVQTEVKSIHLDNRQPARRKHMIEFWEELLLSAAEQLVLAG
KVEAATVAGMRTELQAVRNDPDAVFFFAFVQARASPY