Protein Info for LRK53_RS16350 in Rhodanobacter sp000427505 FW510-R12

Annotation: group II intron reverse transcriptase/maturase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 442 TIGR04416: group II intron reverse transcriptase/maturase" amino acids 40 to 405 (366 residues), 341.3 bits, see alignment E=3.3e-106 PF00078: RVT_1" amino acids 97 to 319 (223 residues), 114 bits, see alignment E=8.3e-37 PF08388: GIIM" amino acids 340 to 410 (71 residues), 54.9 bits, see alignment E=7.2e-19

Best Hits

KEGG orthology group: None (inferred from 55% identity to bja:bll8195)

Predicted SEED Role

"Retron-type RNA-directed DNA polymerase (EC 2.7.7.49)" (EC 2.7.7.49)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.49

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (442 amino acids)

>LRK53_RS16350 group II intron reverse transcriptase/maturase (Rhodanobacter sp000427505 FW510-R12)
MSLGTSPEKVRTLQTALQAKAKAEPTARFHSLWDKVCRTDVLDEAYRRCRANHGAPGSDG
ERFEHIEDHGRGCWLERLQQELRAKSYRPMPLLRVWIPKANGGERPLGIPTIRDRVVQMA
VLLVIGPIFDEDLSPRQFGFRPGRDAKMALRCIHFGITQRGAREVVDADLSDYFNTIPHG
DLMRCVARRIADGTLLAMIRRWLDAAVMERRPQGVRISTEAKSHHRGTPQGGIISPLLAN
LYFRRFMLAWHRFGYAQELGAEVVNYADDFVILCPSGRGERALEVVRHLMTQLGLTVNEK
KTRLVRLPAERFDFLGYTVGRFFGKDGRPYWGSAPSKKAIKSVLRKVHDATSSRWFNKDV
SSRIDELNPLLRGWAGYFNQGPVSSSYRLVQDYTRRRLRIWLMRKQGRKGTGYRQYSDQC
LHEKWGLIRLTSPRMNLSNAKV