Protein Info for LRK53_RS16305 in Rhodanobacter sp000427505 FW510-R12

Annotation: penicillin-binding protein activator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 643 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF04348: LppC" amino acids 54 to 602 (549 residues), 248.8 bits, see alignment E=1.1e-77 PF13458: Peripla_BP_6" amino acids 255 to 452 (198 residues), 43.4 bits, see alignment E=3.7e-15

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (643 amino acids)

>LRK53_RS16305 penicillin-binding protein activator (Rhodanobacter sp000427505 FW510-R12)
MRFMRLSRVAATALLAALVLVACVPANTPRSPTELAAAQSAEALSRQGQFDQAAQAWLAL
AAQSRGHADSYRLLAAEAWREEGQLDRAIPVLADIKRQRLSGDEPLRFDLLQAELALDRH
DAATALRLTTQPNVTVPAPLQLRLLEWRARAMAASGDRWGAARTRVQMDGQLSGYDHSQN
RQQVLDLLGQVGVDSLKQRAAAMQRGDRMLPWVNEALSRLGVAVAQPSPELQQPVGTLLP
GADANVREGYKAPSQVALLLPSDGNYAAASTAIREGFFAAYLDAGRNHAPRPSVRVYDSQ
GTADGAVKAYQQAVSDGARLVVGPLTRGEVAAVFSQPRLPVPLLALNHPDDKQLPAGDAS
EFGLLPETEGAQAADHMVERGLRRVYAVVSTDDFAQRAAGAFKAELAARGGELAGMVTLP
PGVTSYASLIAGLKLPAGTSAAAAPGQPAAAGTTTAPAASGAVGDTGIFISMRPEQARLL
LPQLRIAQVNLPVFATSHVYEGSDDVAANRDLDGVEFCDAPWLFDAQPGLPNHDGIAARL
PAARGGAARLFAFGMDAWNLVPYLEWLRAHPGSYVPGASGQLAADQFGRVRRVLIWAQFQ
NGLARPLGGSLQLDDAPSNAPPASAEPAPAGSAPSGTFQPAAN