Protein Info for LRK53_RS15810 in Rhodanobacter sp000427505 FW510-R12

Annotation: LysR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF00126: HTH_1" amino acids 5 to 63 (59 residues), 73.3 bits, see alignment E=1.2e-24 PF03466: LysR_substrate" amino acids 88 to 293 (206 residues), 144.4 bits, see alignment E=3.4e-46

Best Hits

Swiss-Prot: 38% identical to LTRA_KLEPN: Probable HTH-type transcriptional regulator LtrA (ltrA) from Klebsiella pneumoniae

KEGG orthology group: None (inferred from 63% identity to rfr:Rfer_2533)

Predicted SEED Role

"Transcriptional regulator, LysR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (305 amino acids)

>LRK53_RS15810 LysR family transcriptional regulator (Rhodanobacter sp000427505 FW510-R12)
MDKFQEMASFVAVVEAGSFVGAAEATGLSKAAVSRHVAELEQRLGARLLQRTTRRLSLTD
DGQLFFARAKEMLAAIDEAESEISSRSGEPSGRLRINAPLSFGVLQLAPLWPRFAQLYPK
VSLDIELSDRVVDLVEEGYDLAVRITNLPSSQLVSRQLASTRMIACASPSYLAQHGTPQQ
PQELAQHEVISYSYFAARDEWTFTAPDGSPAVVRTRTRIHANNGDTCRAAALEHQGIILQ
PDFIVADDLRRGDLVELMPTYHAMTLGIHAVYPSRKHLPIKTRRLVDFLVEALAVPGWTI
GHALD