Protein Info for LRK53_RS14990 in Rhodanobacter sp000427505 FW510-R12

Annotation: chemotaxis response regulator CheY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 135 PF00072: Response_reg" amino acids 7 to 121 (115 residues), 102.3 bits, see alignment E=8.7e-34

Best Hits

Swiss-Prot: 73% identical to CHEY_PSEAE: Chemotaxis protein CheY (cheY) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03413, two-component system, chemotaxis family, response regulator CheY (inferred from 77% identity to spc:Sputcn32_2558)

Predicted SEED Role

"Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (135 amino acids)

>LRK53_RS14990 chemotaxis response regulator CheY (Rhodanobacter sp000427505 FW510-R12)
MDKNMKILVVDDFSTMRRIVRNLLVELGFSNPLIQEADDGESALAMLRSQPFDLVVTDWN
MPNMTGIDLLRAIRGEDALKCLPVLMVTAENNRDQIIAAAQAGVNGYIVKPFTAVTLKEK
LTKIFERIAASGVSA