Protein Info for LRK53_RS14935 in Rhodanobacter sp000427505 FW510-R12

Annotation: chemotaxis protein CheA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 671 PF01627: Hpt" amino acids 10 to 104 (95 residues), 54 bits, see alignment E=3.2e-18 PF02895: H-kinase_dim" amino acids 281 to 343 (63 residues), 72.5 bits, see alignment E=6.3e-24 PF02518: HATPase_c" amino acids 393 to 528 (136 residues), 62.2 bits, see alignment E=1.2e-20 PF01584: CheW" amino acids 534 to 662 (129 residues), 92.1 bits, see alignment E=5.1e-30

Best Hits

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (671 amino acids)

>LRK53_RS14935 chemotaxis protein CheA (Rhodanobacter sp000427505 FW510-R12)
MATVDLTQFHKTFFEESLEGLDAMEAALLALDSGSTDHELVHTIFRAAHSIKGGAATFGF
ADVAAFTHVAESLLEEVRSERRAVDTALVDLLLRSVDCLRAMLARSAGGQPAADADSETL
RGELLRLASGEAVAAPAAVASGVASASGWDIRFVALPHLLQTGNDPLRLFRELEQLGRLE
VRRAFVLDSAPARLAELDPSQCHLGWELRLHGAVARGDVDAVFDWLDGDCELAIEALPGE
TSATAADPVAMAAPATAPVPAAAAPPARETATVRAASGEGSSIRVGVDKVDALINMMGEL
VITQSMLSDIGENFRPSQLERLREGLLQLERTTRELQESVMRIRMLPIGSVFNRFPRLVR
DLERKLGKQVRLELHGEHTELDKTVLEKIGDPLVHLVRNAIDHGLELPAQRKAAGKPENG
TLKLNAYHEGGNIVVQISDDGAGLNRAAIVAKAQQRGLLGAGQEPSDAEVAELIFQPGFS
TAAQATDLSGRGVGMDVVRRNVRDLGGSVGVKSEAGKGSVFTIALPLTLAIIDGLVTAVG
DERYIVPLTSIVESLRLKPEAVRRITGGGEVFHFREEYLPIMRLHRAFGCADAVTEIERG
IVVVIEDAGRRMGLLVDDLLGQQQAVIKSLDAHYRRVQGISGATILSDGSVALIVDVGGV
VRLGQRSKAAA