Protein Info for LRK53_RS14400 in Rhodanobacter sp000427505 FW510-R12

Annotation: TetR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 202 transmembrane" amino acids 85 to 101 (17 residues), see Phobius details amino acids 158 to 177 (20 residues), see Phobius details PF00440: TetR_N" amino acids 19 to 63 (45 residues), 33.8 bits, see alignment 5.9e-12 PF17932: TetR_C_24" amino acids 85 to 170 (86 residues), 36.9 bits, see alignment E=9.5e-13 PF14246: TetR_C_7" amino acids 97 to 186 (90 residues), 28.5 bits, see alignment E=3.3e-10 PF17922: TetR_C_17" amino acids 118 to 179 (62 residues), 26.3 bits, see alignment E=1.9e-09 PF16925: TetR_C_13" amino acids 120 to 185 (66 residues), 42.8 bits, see alignment E=1.6e-14

Best Hits

KEGG orthology group: None (inferred from 73% identity to maq:Maqu_1250)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (202 amino acids)

>LRK53_RS14400 TetR family transcriptional regulator (Rhodanobacter sp000427505 FW510-R12)
MDIQRKHLPADERRAVTIEAVIKLAAEQNPSEITTAAIATSMKLTQGALFRHFPSKDAIW
QAVMEWVADHLLARVERAARDAPGPLAALEAMFMAHIAFVAEHAGVPRMLFGELQRAENT
AAKRMVQTMIRRYGERLRTLIEEGKAAGELDPQLDPTAAATLFIGSIQGLVMQALLAGDT
RHMRQEAAGAFAIYRRGIARAA