Protein Info for LRK53_RS13690 in Rhodanobacter sp000427505 FW510-R12

Annotation: catalase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 480 PF00199: Catalase" amino acids 9 to 389 (381 residues), 643.8 bits, see alignment E=1e-197 PF06628: Catalase-rel" amino acids 417 to 476 (60 residues), 80.5 bits, see alignment E=8.4e-27

Best Hits

Swiss-Prot: 71% identical to CATA_BORPA: Catalase (katA) from Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 72% identity to hau:Haur_0032)

MetaCyc: 53% identical to catalase monomer (Homo sapiens)
Catalase. [EC: 1.11.1.21, 1.11.1.6]; 1.11.1.6 [EC: 1.11.1.21, 1.11.1.6]

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.11.1.21 or 1.11.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (480 amino acids)

>LRK53_RS13690 catalase (Rhodanobacter sp000427505 FW510-R12)
MSQNRKTLTTDAGAPVSDNQNSLTAGPRGPLLVQDVALFEKHAHFNRERIPERVVHAKAS
AAFGTLTITRDITKYTRARVFKPGTQTPMLARFSTVAGERGAADAERDVRGFALKFYTEE
GNWDLVGNNTPVFFIRDPYKFPDFIHTQKRDPRTNMRNATAMWDYWSLSPESLHQVTTLM
SDRGIPATLRHMHGFGSHTYGFWNEAGERHWVKFHFKTQQGIRNLSNAEAAKLIGEDRES
HQRDLYESIERKDFPKWTLYVQLMPEADAEKTSYNPFDLTKVWPHKDYPLIEVGVMELNR
NPGNYFAQVEQSSFSPANVVPGIGFSPDKVLQFRLFSYADAARYRLGANHDQLPVNQPRC
PVHNYARDGSMRYGDNGGGSVNYEPNSFGGPVEDPSVKEPPLKISGDADRYDHRAGNDDY
TQPGDLFRLMSDDQKQQLFDNIVAAMQGVPEEIIRRQLGHFAKADPAYAAGVAKALGLAI